Table 2. Comparative analysis of demographic, clinical, and biomarker variables between early and late-stage colorectal cancer patients.
| Characteristics | Early | Late | P value |
|---|---|---|---|
| n | 245 | 174 | |
| Age, median (IQR) | 58 (45, 73) | 57.5 (46, 75.75) | 0.845 |
| Gender, n (%) | 0.395 | ||
| Female | 115 (27.4%) | 89 (21.2%) | |
| Male | 130 (31%) | 85 (20.3%) | |
| Family_History, n (%) | 0.271 | ||
| Yes | 119 (28.4%) | 94 (22.4%) | |
| No | 126 (30.1%) | 80 (19.1%) | |
| Smoking, n (%) | 0.149 | ||
| Yes | 112 (26.7%) | 92 (22%) | |
| No | 133 (31.7%) | 82 (19.6%) | |
| Alcohol_Consumption, n (%) | 0.405 | ||
| No | 134 (32%) | 88 (21%) | |
| Yes | 111 (26.5%) | 86 (20.5%) | |
| Diet, n (%) | 0.556 | ||
| Balanced | 84 (20%) | 59 (14.1%) | |
| High-fat | 72 (17.2%) | 59 (14.1%) | |
| Vegetarian | 89 (21.2%) | 56 (13.4%) | |
| Symptoms, n (%) | 0.149 | ||
| Yes | 112 (26.7%) | 92 (22%) | |
| No | 133 (31.7%) | 82 (19.6%) | |
| Treatment_History, n (%) | 0.591 | ||
| Surgery | 64 (15.3%) | 48 (11.5%) | |
| Radiation | 64 (15.3%) | 41 (9.8%) | |
| Chemotherapy | 53 (12.6%) | 46 (11%) | |
| None | 64 (15.3%) | 39 (9.3%) | |
| Serum_Ferritin, mean ± sd | 147.57 ± 29.771 | 181.62 ± 28.887 | <0.001 |
| CA_19_9, mean ± sd | 19.676 ± 5.3808 | 24.701 ± 5.4809 | <0.001 |
| CEA, mean ± sd | 3.022 ± 1.0698 | 3.997 ± 1.0053 | <0.001 |
Notes.
- IQR
- Interquartile Range, representing the range between the 25th and 75th percentiles
- n (%)
- Number and percentage of patients in each category
- P value
- Statistical significance, with values less than 0.05 indicating significant differences between early and late-stage groups
- sd
- Standard deviation, indicating the variability around the mean value of biomarkers