Table 2.
Cumulative Incidence of Nephrology Referral Within 12 Months From Albuminuria Detection, Among Individuals Meeting Referral Criteria
| After Newly Detected Elevated Albuminuria | After Confirmed Elevated Albuminuria | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Albuminuria Level | Albuminuria Level | |||||||||
| Moderateb | Severec | Very Severed | Moderateb | Severec | Very Severed | |||||
| Swedish criteriae | 5,795 | 28% (27–30) | 28% (26–29) | 23% (21–25) | 37% (34–39) | 3,688 | 42% (40–43) | 32% (30–34) | 44% (41–48) | 66% (62–69) |
| Dipstickf | 2,831 | 11% (10–12) | 15% (13–17) | 7% (6–9) | 9% (7–12) | 1,470 | 22% (20–24) | 15% (13–18) | 24% (19–29) | 43% (37–50) |
| Quantitative methodf | 2,964 | 45% (43–47) | 37% (35–40) | 44% (41–48) | 64% (60–68) | 2,218 | 55% (53–57) | 45% (42–48) | 56% (51–60) | 76% (72–79) |
| KDIGO criteriag | 5,365 | 26% (24–27) | 20% (19–21) | 39% (35–42) | 58% (53–62) | 6,707 | 32% (31–33) | 30% (29–32) | 25% (23–27) | 44% (42–47) |
a
12-Month cumulative incidence (95% CI).
b
Moderate albuminuria: 30–299 mg/g.
c
Severe albuminuria: 300–999 mg/g.
d
Very severe albuminuria: ≥1,000 mg/g.
e
Based on a combination of age, albumin-creatinine ratio, and eGFR thresholds (see Table S2).
f
Type of test at first detection for individuals with newly detected albuminuria, and type of test at albuminuria confirmation for individuals with confirmed albuminuria.
g
Estimated GFR < 30 mL/min per 1.73 m2 or refractory hypertension after newly detected albuminuria; eGFR < 30 mL/min per 1.73 m2, refractory hypertension or sustained albuminuria ≥ 300 mg/g at retesting.