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. 2026 May 1;163:76. doi: 10.1186/s41065-026-00686-7

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© The Author(s) 2026

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Validation of STEAP2-related gene expression. A Heatmap showing differential expression of selected genes in control and ginkgetin-treated 5637 cells. B Quantitative analysis of gene expression changes in 5637 cells following ginkgetin treatment. C Heatmap illustrating gene expression alterations in HT-1376 cells. D Statistical analysis of gene expression levels in HT-1376 cells after ginkgetin treatment. E Relative mRNA expression of STEAP2 and apoptosis-related genes under different experimental conditions in 5637 cells. F Quantitative analysis of STEAP2 and BCL-2/BAX expression in HT-1376 cells