. Author manuscript; available in PMC: 2026 Jun 24.

Published in final edited form as: Am J Psychiatry. 2025 Feb 1;182(2):187–197. doi: 10.1176/appi.ajp.20240069

TABLE 1.

Baseline demographic and drinking characteristics^a

	AUD− (N=101)				AUD+ (N = 120)
	DEP− N=56		DEP+ N=45		DEP− N=56		DEP+ N=64
	N	%	N	%	N	%	N	%	Significance

Sex assigned at birth (male)	27	48.2	23	51.1	34	60.7	36	56.3	ns
Race (White)	38	67.9	34	75.6	46	82.1	47	73.4	ns
Family history of AUD (positive)	7	12.5_^a	18	40.0_^b	24	42.9_^b	31	48.4_^b	Group × Cohort, p<0.05

	Mean	SD	Mean	SD	Mean	SD	Mean	SD

Age (years)	27.7	3.7	26.7	3.8	26.7	3.8	26.8	4.1	ns
Education (years)	16.9_^a	1.8	16.5_^a	1.9	15.6_^b	1.7	15.8_^b	1.9	Group, p<0.001
DSM-5 AUD symptoms (past year)	0.3a	0.5	0.4_^a	0.5	4.1_^b	1.7	4.5_^b	2.3	Group, p<0.001
AUDIT (total score)	5.9_^a	2.8	6.3_^a	2.9	14.8_^b	5.1	17.9_^c	5.3	Group × Cohort, p<0.05
Age at first alcohol drink (years)	17.5_^a	2.3	16.6_^a	2.2	16.0_^b	2.1	16.0_^b	2.4	Group, p<0.001
Drinks per drinking day (past month)	2.5_^a,^c	1.3	2.3_^b,^d	0.9	6.6_^b,^c	2.9	5.4_^b,^d	2.4	Group, Cohort, ps<0.01
Drinks per week (past month)	8.0_^a,^c	6.8	6.2_^b,^d	4.4	28.7_^b,^c	16.4	23.9_^b,^d	12.2	Group, Cohort, ps<0.05
% drinking days (past month)	42.4_^a	20.4	37.0_^a	18.6	61.8_^b	18.1	64.7_^b	17.6	Group, p<0.001
% heavy drinking days (past month)	7.9_^a	12.1	4.8_^a	8.6	41.4_^b	21.3	37.4_^b	20.6	Group, p<0.001
% high intensity days (past month)	0.8_^a	3.0	0.4_^a	1.3	18.2_^b	18.6	10.0_^c	15.2	Group × Cohort, p<0.05

Standard drink unit was 14 g ethanol per drink. Heavy drinking defined as consuming ≥4 standard drinks for a woman (≥5 standard drinks for a man). High intensity drinking defined as consuming ≥8 standard drinks for a woman (≥10 standard drinks for a man). Differing subscripts (a-d) denote significant differences for main effects of group (AUD), cohort (DEP), or their interaction.