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. 2026 Jun 16;34(7):6. doi: 10.32604/or.2026.078483
ABY affibody
ADAM10 a disintegrin and metalloproteinase domain 10
ADC antibody drug conjugate
ADCC antibody dependent cellular cytotoxicity
ADCN affibody-drug conjugate nanoagent
ALCL anaplastic large cell lymphoma
ALL acute lymphoblastic leukemia
AML acute myeloid leukemia
ATL adult T-cell leukemia/lymphoma
BC breast carcinoma/cancer
BCMA B-cell maturation antigen
BsAb bispecific antibody
BTN3A1 butyrophilin 3A1
BTN2A1 butyrophilin 2A1
BV brentuximab vedotin
CAR chimeric antigen receptor
CD cluster of differentiation
CDC complement dependent cytotoxicity
CDK cyclin dependent kinase
Cet cetuximab
CLL Chronic lymphocytic leukemia
CR complete response
CRBN cereblon
CRISPR Clustered Regularly Interspaced Short Palindromic Repeats
CRC colorectal carcinoma
CRS cytokine release syndrome
CTL cytotoxic T lymphocytes
CTLA4 Cytotoxic T-Lymphocyte Antigen 4
CXCR4 C-X-C motif chemokine receptor 4
Cu cuprum
DAR drug antibody ratio
DARPins designed ankyrin repeat proteins
DFS disease free survival
DLBCL diffuse large B-cell lymphoma
DM1 mertansine/emtansine
DMAPP dimethylallyl pyrophoshates
DNA deoxyribonucleic acid
DOTA 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid
EBV epstein barr virus
EGFR epidermal growth factor receptor
EMA European Medicines Agency
ERBB Epidermal Growth Factor Receptor family
EXA exatecan mesylate
Fab fragment antigen binding
FASL FAS ligand
FDA food and drug administration
FISH fluorescence situ hybridization
FKBP12 FK506 binding protein 12
GSPT1 G1 to S phase transition 1
HER2 human epidermal growth factor receptor 2
HER3 human epidermal growth factor receptor 3
HL Hodgkin lymphoma
HTLV-1 human T-cell leukemia virus type 1
IBA ibandronic acid
ICAM1 Intercellular adhesion molecule 1
ICI immune checkpoint inhibitor
Ig immunoglobulin
IFN interferon
IHC immunohistochemistry
IMQ imiquimod
IPP isopentenylpyrophosphate
LAMP1 lysosomal associated membrane protein 1
LFA1 lymphocyte function associated antigen 1
LFA3 lymphocyte function associated antigen 3
Lu lutetium
mAbs monoclonal antibodies
MACs molecular glue antibody conjugates
mBC metastatic breast carcinoma
MDS myelodysplastic syndrome
MF mycosis fungoide
MAPK mitogen-activated protein kinase
MMAE monomethyl auristatin E
MMAF monomethyl auristatin F
Mo/MΦ monocyte/macrophage
N-BP aminobisphosphonate
NHL non-Hodgkin lymphoma
NRG neuregulin
NFkB nuclear factor kappa B
NK natural killer
NOTA 1,4,7-triazacyclononane-1,4,7-triacetic acid
NSCLC non-small cell lung cancer
NSG NOD SCID gamma
ORR overall response rate
pAg phosphoantigen
PBMC peripheral blood mononuclear cells
PC prostate carcinoma
PDAC pancreatic adenocarcinoma
PD1 programmed cell death protein 1
PDL1 programmed cell death protein ligand 1
PDO patient-derived organoid
PDX patient-derived xenografts
PET positron emission tomography
PI3K phospho inositol 3 kinase
PFS progression-free survival
PR partial response
PTCL peripheral T cell lymphoma
RAB11A Ras-related protein Rab-11A
RIS risedronic acid
RIT radio immunotherapy
RLN2 relaxin 2
r/r relapse/refractory
scFv single-chain variable fragment
SCID severe combined immunodeficiency
SCLC small cell lung cancer
SD stable disease
SMMC succinimidyl-4-(N-maleimidomethyl cyclohexane-1carboxylate
SNX10 sorting nexin 10
SPECT Single Photon Emission Computed Tomography
Tb terbio
TDXd trastuzumab deruxtecan
TDM1 trastuzumab mertansine/emtansine
TIL tumor infiltrating lymphocyte
TNF tumor necrosis factor
TNFRSF tumor necrosis factor receptor superfamily
TME tumor microenvironment
TPL triptolide
TR trastuzumab resistant
VC valine-citrulline
ZA zoledronic acid