Table 2.
Summary of median and mean overall survival in AT/RT (BT12) orthotopic xenografts treated with PECE HGs loaded at 30 or 50% (w/w) with combined CHIR and RBV
| Treatment following tumour resection | n | Mean survival (days)a | Median survival (days) | SEM | LTS | %LTS |
|---|---|---|---|---|---|---|
| Control | 8 | 36.9 | 18.0 | 13.3 | 0 | 0 |
| Blank PECE | 8 | 22.8 | 19.5 | 3.1 | 0 | 0 |
| 10 Gy XRT | 10 | 57.3 | 59.0 | 10.1 | 0 | 0 |
| PECE with (CHIR + RBV) @ 30% (w/w) | 10 | 70.5 | 56.0 | 14.5 | 1 | 10 |
| PECE with (CHIR + RBV) @ 50% (w/w) | 10 | 54.2 | 45.5 | 11.6 | 1 | 10 |
aEstimation is limited to the longest survival time if censored