5-HT3	5-hydroxytryptamine type 3
AAV	adeno-associated virus
ABR	auditory brainstem response
ACEMg	vitamins A, C, E, and magnesium
AE	adverse event
BLB	blood–labyrinth barrier
CI	cochlear implant
CRISPR-Cas9	clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9
CSF	cerebrospinal fluid
DFNB9	autosomal recessive deafness 9
FDA	Food and Drug Administration
GPx	glutathione peroxidase
GSI	gamma-secretase inhibitor
HBOT	hyperbaric oxygen therapy
HDVC	high-dose vitamin C
HES	hydroxyethyl starch
IC	intracochlear
IGF-1	insulin-like growth factor 1
IRB	Institutional Review Board
ISSNHL	idiopathic sudden sensorineural hearing loss
IT	intratympanic
ITS	intratympanic steroids
IV	intravenous
JNK	c-Jun N-terminal kinase
LDL	low-density lipoprotein
LDP	Liuwei Dihuang Pill
mTOR	mammalian target of rapamycin
NAC	N-acetylcysteine
NCE	new chemical entity
OSF	Open Science Framework
OTOF	otoferlin gene
PGE1	prostaglandin E1
PI3K/Akt	phosphoinositide 3-kinase/protein kinase B
PRISMA-ScR	Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews
PRP	platelet-rich plasma
PTA	pure-tone audiometry
Q-TER	water-soluble coenzyme Q10 formulation
RA	Radix Astragali
RCT	randomized controlled trial
ROS	reactive oxygen species
SNHL	sensorineural hearing loss
SSNHL	sudden sensorineural hearing loss
STS	sodium thiosulfate
TTS	temporary threshold shift
WHO	World Health Organization