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. 2026 Jun 20;14(6):1394. doi: 10.3390/biomedicines14061394
5-HT 5-hydroxytryptamine (serotonin)
6-OHDA 6-hydroxydopamine
AAV Adeno-associated viral vector
AC1/Cg1 Anterior cingulate cortex, subdivision 1
AC2/Cg2 Anterior cingulate cortex, subdivision 2
AMPA α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
ATP8A1 ATPase phospholipid transporting 8A1
BDNF Brain-derived neurotrophic factor
BOLD Blood-oxygen-level-dependent
CADPS2 Calcium dependent secretion activator 2
Cg Cingulate cortex
DA Dopamine/dopaminergic
DLB Dementia with Lewy bodies
dlPFC Dorsolateral prefrontal cortex
DMN Default mode network
E/I Excitatory/inhibitory
EPSC Electrically evoked excitatory postsynaptic current
GABA Gamma-aminobutyric acid
GABARAP Gamma-aminobutyric acid receptor-associated protein
GAD Glutamic acid decarboxylase
Glu Glutamate
GluA1/GluA2 AMPA receptor subunits 1 and 2
GluN1/GluN2A/B NMDA receptor subunits 1, 2A, and 2B
IL Infralimbic cortex
L5/6 Layer 5/Layer 6
LC Locus coeruleus
LBDs Lewy body dementias
LTP Long-term potentiation
mEPSC Miniature excitatory postsynaptic current
mPFC Medial prefrontal cortex
MPTP 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
mTOR Mammalian target of rapamycin
NA Noradrenaline
NAC Non-amyloid-β component
NMDA N-methyl-D-aspartate
NSF N-ethylmaleimide-sensitive factor
PD Parkinson’s disease
PDD Parkinson’s disease dementia
PD-MCI Parkinson’s disease-associated mild cognitive impairment
PET Positron emission tomography
PFF Pre-formed fibril
PrL Prelimbic cortex
PSD-95 Postsynaptic density protein 95
PV Parvalbumin
rab27B Ras-related protein
RN Raphe nuclei
rs-fMRI Resting-state functional magnetic resonance imaging
SN Substantia nigra
SNc Substantia nigra pars compacta
SNARE Soluble N-ethylmaleimide-sensitive factor attachment protein receptor
SNCA Synuclein alpha gene
SOC α-Synuclein origin site and connectome
SPN Striatal spiny projection neuron
SST Somatostatin
SV Synaptic vesicle
SV2A/2B Synaptic vesicle glycoprotein 2A/2B
TrkB Tropomyosin receptor kinase B
VAMP2 Vesicle-associated membrane protein 2
VGAT Vesicular GABA transporter
VGLUT1 Vesicular glutamate transporter-1
VGLUT2 Vesicular glutamate transporter-2
vmPFC Ventromedial prefrontal cortex
VTA Ventral tegmental area
WT Wild-Type
α-Syn α-Synuclein
1H-MRS Proton magnetic resonance spectroscopy