TPBC	Triple-Positive Breast Cancer
ER	Estrogen Receptor
PR	Progesterone Receptor
HER2 = EGFR2	Human Epidermal Growth Factor Receptor 2
BC	Breast cancer
NCCN	National Comprehensive Cancer Network
NCBI	National Center for Biotechnology Information
EGFR = HER1	Epidermal Growth Factor Receptor
HER3	Human Epidermal Growth Factor Receptor 3
HER4	Human Epidermal Growth Factor Receptor 4
PI3K	phosphatidylinositol 3-kinase
AKT	a serine/threonine protein kinase
mTOR	[Ser/Thr kinase] mechanistic target of rapamycin
MAPK	mitogen-activated protein kinases
ERK	Extracellular Signal-Regulated Kinase
ErbB	Erythroblastic Leukemia Viral Oncogene Homolog [family]
ADCC	Antibody-dependent cytotoxicity
Fc-mediated immunity	Constant fragment [of antibodies that mediates downstream effector functions via its interaction with Fc-receptors on (innate) immune cells]
CDK4	Cyclin-Dependent Kinase 4
TGF-α	Transforming Growth Factor Alpha
EGF	Epidermal Growth Factor
Met	methionine
BIRC5	baculoviral inhibitor of apoptosis repeat-containing 5
TRAF4	Tumor Necrosis Factor Receptor-Associated Factor 4
PTEN	Phosphatase and Tensin homolog
PIK3CA	gene encodes for the p110 alpha (p110α) protein, catalytic subunit of PI3K
CD55	Decay-accelerating factor (CD55 = DAF)
CD59	[Protective protein]
Wnt3	Wnt refers to a family of secreted signaling proteins involved in various biological processes, particularly in cell communication and development. The name “Wnt” is a portmanteau derived from “Wingless”, a gene from the fruit fly Drosophila, and “Int-1”, a proto-oncogene from mice.
PDGFRA	gene encodes for PDGFRα
PDGFRα	platelet-derived growth factor receptor alpha
MUC1-C	C-terminal subunit for MUC1 protein
IGF-1R	Insulin-like Growth Factor 1 Receptor
P85β	regulatory subunit of PI3K
P110	isoforms of the class-1A PI3K signaling pathway
Yes1	non-receptor protein tyrosine kinase
Src	non-receptor protein tyrosine kinase
OXPHOS	Oxidative Phosphorylation
NDUFA4L2	NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2
ROS	Reactive Oxygen Species
LMO4	LIM Domain Only 4
YB-1	Y-box Binding Protein 1
CD44	Cluster of Differentiation 44
IL6	Interleukin-6
BCL-2	B-cell Lymphoma 2
P95her2	Truncated HER2 receptor (p95HER2)
HERA program	HERceptin Adjuvant trial
AXL	AXL Receptor Tyrosine Kinase
GSK3	Glycogen Synthase Kinase 3
mTOR-C1	mTOR complex 1
Wnt	Wingless/Integrated
NFGR	Nerve Growth Factor Receptor
MUSK	Muscle-Specific Kinase
VEGFR1	Vascular Endothelial Growth Factor Receptor 1
PDGFRA	Platelet-Derived Growth Factor Receptor Alpha
PDGFβ	Platelet-Derived Growth Factor Beta
EPHA2	Ephrin Type-A Receptor 2
EPHB2	Ephrin Type-B Receptor 2
Fak = FAK1	Focal adhesion kinase 1
PBC	primary breast cancer
SERMs	Selective Estrogen Receptor Modulators
MUC1	Mucin-1
AIB1	Amplified in Breast Cancer 1 (SRC-3)
SERD	Selective Estrogen Receptor Degrader
CXXC4	CXXC Finger Protein 4
PBCC	primary basal cell carcinoma
MED1	Selective Estrogen Receptor Degrader
Eph	Eph receptors
AKT1	AKT Serine/Threonine Kinase 1
CSC	cancer stem cells
TGF-β	Transforming Growth Factor Beta
STAT3	Signal transducer and activator of transcription 3
NF-kB	Nuclear Factor kappa B
SMAD	Transcription factors proteins for TGF-β. SMAD is a portmanteau from SMA (small body size) and MAD (Mothers Against Decapentaplegic).
AURKA	Aurora kinase A
TrkB	Tropomyosin Receptor Kinase B
SOX2	SRY-Box Transcription Factor 2
CD24	Cluster of Differentiation 24
MHC	Major Histocompatibility Complex
HLA	Human Leukocyte Antigen
CD4/6	Cyclin-Dependent Kinases 4/6
AI	artificial intelligence
KEEG	Kyoto Encyclopedia of Genes and Genomes (KEGG)
hsa:2064	Human gene identifier (ERBB2/HER2)
JAK	Janus Kinase
TKI	tyrosine kinase inhibitors
EMT	epithelial–mesenchymal transition
PDX	Patient-Derived Xenograft
TP-0903	TP-0903 (drug candidate)
RNA	Ribonucleic acid
HDAC	histone deacetylase
DNA	Deoxyribonucleic Acid
DNMT	DNA methyltransferase
HMG-CoA	3-Hydroxy-3-Methylglutaryl-Coenzyme A
RAS	Rat Sarcoma Virus Oncogene
RHO	Ras Homologous Protein
RAC	Ras-related C3 botulinum toxin substrate
GLI	Glioma-associated Oncogene
Hh	Hedgehog
ATPase	Adenosine Triphosphatase
AMPK	Adenosine Monophosphate Kinase