AUC	Area under the curve
AI	Artificial intelligence
BRAF	B-Raf proto-oncogene, serine/threonine kinase
CAF	Cancer-associated fibroblast
CITE-seq	Cellular indexing of transcriptomes and epitopes by sequencing
CD1a	Cluster of differentiation 1a
CD3	Cluster of differentiation 3
CD4	Cluster of differentiation 4
CD8	Cluster of differentiation 8
CD20	Cluster of differentiation 20
CD68	Cluster of differentiation 68
CD95	Cluster of differentiation 95
CE	Conformité Européenne
CODEX	Co-detection by indexing
cDC1	Conventional type 1 dendritic cells
CTLA-4	Cytotoxic T-lymphocyte-associated protein 4
ctDNA	Circulating tumour DNA
CXCL10	C-X-C motif chemokine ligand 10
CXCL9	C-X-C motif chemokine ligand 9
CXCR3	C-X-C motif chemokine receptor 3
CycleGAN	Cycle-consistent generative adversarial network
DNA	Deoxyribonucleic acid
DSP	Digital spatial profiling
DSP-WTA	Digital spatial profiling whole transcriptome atlas
eTILs	Electronic tumour-infiltrating lymphocytes score
FOXP3	Forkhead box P3
GEP	Gene expression profile
GeoMx	GeoMx Digital Spatial Profiler platform
H&E	Haematoxylin and eosin
CD38^hi	High CD38 expression
HER2	Human epidermal growth factor receptor 2
IMC	Imaging mass cytometry
IMMUcan	Integrated Immunoprofiling of Large Adaptive Cancer Patient Cohorts
ICI	Immune checkpoint inhibitor
IHC	Immunohistochemistry
iNOS	Inducible nitric oxide synthase
IFN-γ	Interferon gamma
IFQuant	Immunofluorescence quantification software
IL-15	Interleukin 15
IL7R	Interleukin 7 receptor
KRAS	Kirsten rat sarcoma viral oncogene homologue
LAG-3	Lymphocyte-activation gene 3
LDH	Lactate dehydrogenase
MHC I	Major histocompatibility complex class I
mregDC	Mature regulatory dendritic cells
mRNA	Messenger ribonucleic acid
MDM	Monocyte-derived macrophage
MEK	Mitogen-activated protein kinase kinase
mIF	Multiplex immunofluorescence
MDSC	Myeloid-derived suppressor cell
NLR	Neutrophil-to-lymphocyte ratio
NSCLC	Non-small-cell lung cancer
OS	Overall survival
PD-1	Programmed cell death protein 1
PD-L1	Programmed death-ligand 1
PFS	Progression-free survival
QIF	Quantitative immunofluorescence
ROI	Region of interest
RNA	Ribonucleic acid
RNA-seq	RNA sequencing
Treg	Regulatory T-cell
S100B	S100 calcium-binding protein B
SOX10	SRY-box transcription factor 10
sPD-1	Soluble programmed cell death protein 1
sPD-L1	Soluble programmed death-ligand 1
TLS	Tertiary lymphoid structures
TCF4	Transcription factor 4
TCF7	Transcription factor 7
TGF-β	Transforming growth factor beta
TIICs	Tumour-infiltrating immune cells
TIL	Tumour-infiltrating lymphocyte
TME	Tumour microenvironment
TMB	Tumour mutational burden
WSI	Whole-slide imaging