AI	Artificial intelligence
ALT	Alanine aminotransferase
ANGPTL3	Angiopoietin-like protein 3
apo(a)	Apolipoprotein(a)
ApoB	Apolipoprotein B
APOE	Apolipoprotein E
ARH	Autosomal recessive hypercholesterolemia
ARISE	Algorithmic risk inspection for screening elevated Lp(a)
ASCVD	Atherosclerotic cardiovascular disease
ASO	Single-strand antisense oligonucleotide
AST	Aspartate aminotransferase
CAD	Coronary artery disease
CAVS	Calcific aortic valve stenosis
CHD	Coronary heart disease
c-IMT	Carotid intima-media thickness
CTX	Cerebrotendinous xanthomatosis
CVD	Cardiovascular disease
EAS	European Atherosclerosis Society
ELISA	Enzyme-linked immunosorbent assay
ERT	Enzyme replacement therapy
FH	Familial Hypercholesterolemia
GWAS	Genome-wide association study
HDL-c	High-density lipoprotein cholesterol
HeFH	Heterozygous FH
HoFH	Homozygous FH
HSCT	Hematopoietic stem cell transplant
IFCC	International Federation of Clinical Chemistry
K-IV2	Kringle IV type 2
LALD	Lysosomal acid lipase deficiency
LC-MS	Liquid chromatography–mass spectrometry
LDL-c	Low-density lipoprotein cholesterol
LDLR	LDL receptor
LDLRAP1	LDLR adaptor protein 1
LLT	Lipid-lowering therapy
Lp(a)	Lipoprotein(a)
Lp(a)-c	Lipoprotein(a) cholesterol
LIPA	Lysosomal acid lipase
MI	Myocardial infarction
MTTP	Microsomal triglyceride transfer protein
NGS	Next Generation Sequencing
Non-HDL-c	Non-High-density lipoprotein cholesterol
NPC1L1	Niemann–Pick C1-like 1
OxPLs	Oxidized phospholipids
PAD	Peripheral arterial disease
PCSK9	Proprotein convertase subtilisin/kexin type 9
PCSK9i	PCSK9 inhibitors
PRS	Polygenic risk score
siRNA	Small interfering RNA
SNPs	Single-nucleotide polymorphisms
USV	Uncertain significance variant
VLDL	Very low-density lipoprotein
WHO	World Health Organization