FIG. 1.

Representation of the M. tuberculosis genomic region surrounding hbhA. (A) Gene arrangement in the wild-type H37Rv strain. (B) Alteration in the ΔhbhA mutant strain. The ΔhbhA mutant contains a 576-bp in-frame deletion in the hbhA gene. The hbhA gene in the ΔhbhA mutant consists of the first 12 bases of the coding region of hbhA followed by the final 12 bases of the coding region of hbhA. The designations for the gene names were assigned by the Sanger Centre. hbhA is also known as Rv0475. The sizes of the genes are given in base pairs below the gene names, and the number of nucleotides separating the genes is also given in base pairs.