TABLE 1.
Infection (days p.i.)a | IFN-γ concn (ng/ml) in cultures stimulated with indicated antigen
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---|---|---|---|---|
WT
|
μMT
|
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ConA | Chl-Ag | ConA | Chl-Ag | |
Primary (10) | 18.5 ± 10.6 | 32.6 ± 5.6b | 12.8 ± 6.2 | 18.2 ± 4.4b |
Reinfection (5) | 65.8 ± 12.6 | 48.6 ± 7.4 | 54.6 ± 8.8 | 52.4 ± 6.8 |
At the indicated time points, groups of five mice were sacrificed and spleen cell cultures were stimulated with the C. abortus antigens (Chl-Ag; 50 μg/ml) or concanavalin A (ConA; 5 μg/ml). When only medium was added to the spleen cells, no production of IFN-γ was observed. Results are expressed as means ± SD and are from one representative experiment of two independent experiments.
Significant differences (P < 0.01) between μMT and WT mice at the same day p.i.