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. 2026 Jun 22;14(2):36. doi: 10.3390/jmahp14020036
AEMPS Spanish Agency of Medicines and Medical Devices (Agencia Española de Medicamentos y Productos Sanitarios)
AMNOG German Act on the Reform of the Market for Medicinal Products (Arzneimittelmarktneuordnungsgesetz)
ASMR Improvement in the actual benefit
ATMP Advanced therapy medicinal products
EMA European Medicines Agency
EU European Union
G-BA German Federal Joint Committee (Gemeinsamer Bundesausschuss)
HTA Health Technology Assessment
HTDs Health Technology Developers
ITC Indirect treatment comparison
JCA Joint Clinical Assessment
MAIC Matching-adjusted indirect comparison
MS Member States
PICO Population, Intervention, Comparator, Outcomes
RCT Randomised control trial
RE Relative effectiveness
RoB Risk of Bias
SATs Single-arm trials
SMR Rating of actual benefit
TLI Drug technologies with a high level of innovation
TLK Drug technologies with high clinical value