TABLE 1.

Deduced protein sequence identity and similarity of IroN_{E. coli} and its putative plug domain to the Fe transport proteins IroN_Sal, FepA, IreA, FecA, and FhuA

Organism	Homologue	Complete protein		Plug domaina
		% Identityb (ratio)	% Similarityb (ratio)	% Identity (ratio)	P valuec	% Similarity (ratio)	P valued
Salmonella enterica	IroNSal	82 (593/725)	91 (661/725)	92 (130/142)	0.001	98 (139/142)	0.003
E. coli	FepA	52 (375/725)	68 (492/725)	71 (101/142)	<0.001	82 (116/142)	<0.001
E. coli	IreA	27 (197/725)	43 (312/725)	45 (64/142)	<0.001	62 (88/142)	<0.001
E. coli	FecA	21 (152/725)	39 (282/725)	16 (23/142)	>0.10	30 (43/142)	0.06
E. coli	FhuA	18 (127/725)	35 (251/725)	18 (25/142)	>0.10	37 (52/142)	>0.10

^aAs defined by the crystallographic structure for FepA (3), FecA (7), and FhuA (13) (see text).

^bDetermined by CLUSTAL alignments.

^cCompared to the percent identity of the complete protein from the same strain (Fisher's exact test).

^dCompared to the percent similarity of the complete protein from the same strain (Fisher's exact test).