FIG. 4.

Tucaresol enhances the specific antibody response to Mhsp65 following administration of pDNA encoding Mhsp65. Mice (five per group) were injected twice with 20 μg of pDNA per injection as described in Materials and Methods. Mice from the group treated with tucaresol received 1 mg of tucaresol s.c. simultaneously. Two weeks later, the mice were bled, and antigen-specific IgG (a), IgG2a (b), and IgG1 (c) were detected by ELISA.