TABLE 1.

ICC-1132 elicits anamnestic antibody responses in P. falciparum sporozoite-primed mice^a

Priming	Boost	IgG titer for:
		ELISA	IFA
P. falciparum sporozoites	ICC-1132	103,213	327,680
P. falciparum sporozoites	HBc149	1,280	2,560
None	ICC-1132	101	320

^aBALB/c mice were primed with a single injection of 10⁵ P. falciparum sporozoites. Approximately 3 months later, when ELISA GMTs were 970 (range, 320 to 2,560) and pooled sera IFA titer was 1,280, the sporozoite-primed mice were injected with 5 μg of ICC-1132 or HBc. Naïve mice received a single injection of ICC-1132 as control. IgG ELISA and IFA titers were determined 10 days after the boost.