CM	continuous manufacturing
CPPs	critical Process Parameters
PAT	process analytical technology
CMAs	critical material attributes
CQAs	critical quality attributes
HSM	high shear mixer
TSG	Twin-screw granulation
RTD	residence time distribution
PSD	particle size distribution
DS	design space
HCl	hydrochloride
DoE	Design of Experiment
CCD	central composite design
USP	United States Pharmacopeia
CI	Carr’s Index
HPLC	High-performance liquid chromatography
SME	specific mechanical energy
RT	room temperature
AC	accelerated storage
RH	relative humidity
API	active pharmaceutical ingredient
LOD	loss on drying
HR	Hausner Ratio
UV-Vis	ultraviolet-visible
Tween 80	polysorbate 80