BaP	Benzo(a)pyrene
BRET	Bioluminescence resonance energy transfer
CYP450	Cytochrome P450
DCFH-DA	2,7-dichlorofluorescein diacetate
DMEM	Dulbecco’s modified Eagle Medium
DMSO	Dimethyl sulfoxide
EFSA	European Food Safety Authority
ESI	Electrospray ionization
FBS	Fetal bovine serum
FD-IC	Freeze-drying Instant Cascara
FRET	Förster resonance energy transfer
GPCR	G-protein-coupled receptors
IARC	International Agency for Research on Cancer
IC	Instant Cascara
IC 0.0	Instant Cascara without carrier
IC 1.0	Instant Cascara with long-chain inulin
IC 2.0	Instant Cascara with oligofructose-enriched inulin
iNOS	Nitric oxide synthase
LMP	Low-melting-point agarose
LPS	Lipopolysaccharide
MAChRs	Muscarinic acetylcholine receptors
MTT	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NO	Nitric oxide
PBS	Phosphate-buffered saline
PhIP	2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine
PI	Propidium iodide
ROS	Reactive oxygen species
SD	Standard deviation
SD-IC	Spray-drying Instant Cascara
tBOOH	Tert-butyl hydroperoxide