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. 2026 May 22;18(6):634. doi: 10.3390/pharmaceutics18060634
BCS Biopharmaceutics Classification System
BE Bioequivalence
PBPK Physiologically based pharmacokinetic modeling
HBSS Hanks’ balanced salt solution
ESI Electrospray ionization
PET/CT Positron emission tomography/computed tomography
CMS-Na Sodium carboxymethyl starch
HPMC Hydroxypropyl methylcellulose
LC-MS/MS Liquid chromatography/tandem mass spectrometry
Cmax Peak plasma concentration
AZT Zidovudine
API Active pharmaceutical ingredient
Tmax Time to reach Cmax
AUC0–8h Area under the plasma concentration–time curve from time zero to 8 h
T1/2 Elimination half-life
AUC0–∞ Area under the plasma concentration–time curve from time zero to infinity
SOP Standard of Practice
%ID/g The percentage of injected dose per gram of tissue
TEER Transepithelial electrical resistance
PBBM Physiologically based biopharmaceutics modeling
P-gp P-glycoprotein
BCRP Breast cancer resistance protein
T½_g Gastric half-emptying time