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Challenge results
| Immunogen | No. of DF+ lesions/total (%)a | P valueb | No. of ulcerative lesions/total (%) | P valueb |
|---|---|---|---|---|
| Fragment 1 | 8/32 (25) | <0.001 | 12/32 (37.5) | <0.001 |
| Fragment 2 | 22/24 (91.7) | >0.05 | 16/24 (66.7) | <0.001 |
| Fragment 3 | 27/32 (84.4) | <0.025 | 18/32 (56.3) | <0.001 |
| None | 32/32 (100) | 32/32 (100) |
Aspirates were taken from lesions and examined under a dark-field microscope for the presence of treponemes.
Chi-square test comparing test values to unimmunized-control values.
