TABLE 1.

TNF MSM and TNF-α promoter RFLP allele frequencies

Marker and allelea	Frequencyb
	Total sample	Unrelated individuals
TNF MSM
TNFa1	0.031	0.032
TNFa2	0.228	0.208
TNFa3	0.006	0.003
TNFa4	0.079	0.075
TNFa5	0.072	0.051
TNFa6	0.208	0.193
TNFa7	0.104	0.168
TNFa8	0.012	0.008
TNFa9	0.015	0.013
TNFa10	0.137	0.151
TNFa11	0.077	0.070
TNFa12	0.007	0.003
TNFa13	0.021	0.023
TNFa14	0.001	0.000
TNFa15	0.002	0.002
TNF-α promoter RFLP
TNF1	0.848	0.860
TNF2	0.152	0.140

^aFifteen polymorphic alleles of the TNF microsatellite dinucleotide repeat marker upstream of the TNFB gene and two alleles of the RFLP marker at position −307 in the TNF-α promoter were detected.

^bShown are the frequencies of alleles in the entire population (Total sample) and in 301 unrelated individuals.