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Decreased virulence of the pgdA mutant strain. Groups of 7 to 14 mice received an intraperitoneal injection of 102 (A), 103 (B), 104 (C), 105 (D), 106 (E), and 107 (F) CFU of either R36A::pPGDA(SIII) (closed squares) or the control strain R36A(SIII) (open squares). The survival of the mice is shown for the experimental period of 28 days.
