TABLE 2.
P. multocida genes up-regulated during growth within all three infected chickens
| Gene | Precise or predicted function (COGs categorya) | Expression valueb
|
||
|---|---|---|---|---|
| c1 | c2 | c3 | ||
| asnA | Ammonia-dependent asparagine synthetase (E) | 3.22 ± 0.77 | 1.24 ± 0.3 | 2.71 ± 0.37 |
| aspC | Aspartate transaminase (E) | 1.09 ± 0.37 | 1.17 ± 0.3 | 1.51 ± 0.32 |
| dcaA | Unknown (R) | 1.27 ± 1.34 | 2.18 ± 0.43 | 2.86 ± 0.9 |
| dppA | Dipeptide transport system permease (E) | 0.88 ± 0.57 | 1.95 ± 0.45 | 3.5 ± 0.33 |
| gdhA | Glutamate dehydrogenase (E) | 3.01 ± 0.27 | 1.51 ± 0.39 | 3.27 ± 0.91 |
| gltA | Citrate synthase (C) | 1.04 ± 0.39 | 1.35 ± 0.43 | 2.05 ± 0.45 |
| ilvH | Acetolactate synthase (E) | 1.21 ± 0.99 | 1.82 ± 0.41 | 1.33 ± 0.23 |
| napA | Periplasmic nitrate reductase (C) | 2.33 ± 0.26 | 2.13 ± 0.51 | 1.69 ± 0.14 |
| napC | Periplasmic nitrate reductase (C) | 1.97 ± 0.53 | 2.28 ± 0.81 | 1.08 ± 0.85 |
| napF | Periplasmic nitrate reductase (C) | 3.7 ± 0.17 | 2.58 ± 0.17 | 2.29 ± 0.43 |
| PM0092 | Sigma-54 modulation protein (J) | 1.4 ± 0.41 | 0.83 ± 0.1 | 1.63 ± 0.14 |
| PM0287 | Oxidoreductase (R) | 0.99 ± 0.32 | 3.07 ± 0.17 | 2.1 ± 0.3 |
| PM0601 | Carbohydrate transport and metabolism (G) | 0.9 ± 1.18 | 0.76 ± 0.72 | 1.36 ± 1.05 |
| PM1460 | Phosphoglycerate transport system activator (T) | 1.26 ± 1.15 | 1.23 ± 0.4 | 1.29 ± 0.61 |
| ppc | PEP carboxylase (C) | 3.07 ± 0.59 | 1.39 ± 0.49 | 3.04 ± 0.61 |
| ptfA | Type IV fimbrial subunit (N) | 0.89 ± 0.79 | 0.83 ± 0.45 | 0.9 ± 0.44 |
| purH | Purine biosynthesis (F) | 1.26 ± 0.12 | 0.87 ± 0.16 | 1.21 ± 0.25 |
a
COGs functional categories (44). The full functional categories associated with each COGs letter designation are given in the legend to Fig. 3. Where no precise function is apparent from amino acid homology, the general COGs category title is listed under the predicted function.
b
Expression values are expressed as the log2 of (average experimental intensity/average control intensity) ± 1 standard deviation. Therefore, identical experimental and control expression values would be 0.0.