TABLE 2.
Summary of SPATE functions
| SPATE protein | Cleavage of biological substrates
|
Cytopathic effects on HEp-2 cells | |||
|---|---|---|---|---|---|
| Mucin | Pepsin | Factor V | Spectrin | ||
| EspC | − | + | + | + | − |
| EspP | − | + | + | − | − |
| Pet | − | + | + | + | + |
| Sat | − | − | + | + | + |
| SepA | − | − | − | − | − |
| Tsh | + | − | + | − | − |
| Pic | + | − | + | − | − |