TABLE 2.
Chemotactic properties of human antimicrobial peptides
| Peptide | Leukocyte(s) reported to be attracted | Chemotaxis receptor | Reference(s) |
|---|---|---|---|
| α-Defensins | |||
| HNP1 | Monocytes, T cells, dendritic cells | Unknown | 2, 22, 25 |
| HNP2 | Monocytes, T cells, dendritic cells | Unknown | 2, 22, 25 |
| β-Defensins | |||
| hBD1a | Dendritic cells | CCR6 | 24, 27 |
| hBD2 | T cells, dendritic cells, mast cells | CCR6 | 14, 24, 27 |
| hBD3 | Monocytes, dendritic cells | CCR6 | 24 |
| hBD4 | Monocytes | Unknown | 7 |
| Cathelicidins | |||
| LL-37 | Neutrophils, monocytes, T cells, mast cells | FPRL1 | 2, 15, 26 |
a
hBD, human β-defensin.