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. 2026 Jun 15;17:1862214. doi: 10.3389/fendo.2026.1862214

Table 10.

The incidence of amputation and the changes of 25OH-vitD, thyroid function and clinical data in type 2 diabetic foot ( x¯ ± s).

Non-amputation(n=68) Minor amputation(n=7) Major amputation(n=4) F P
Age(year) 61.26 ± 11.37 60.00 ± 10.40 63.25 ± 6.08 0.11 0.89
BMI(kg/m2) 23.77 ± 3.18 23.92 ± 6.04 23.53 ± 1.80 0.22 0.80
DOD(year) 10.71 ± 7.51 9.00 ± 7.84 16.25 ± 7.50 1.25 0.29
HbA1c(%) 9.14 ± 2.73 8.03 ± 3.02 12.00 ± 2.85 2.60 0.08
CRP(mg/L) 44.24 ± 44.97 24.25 ± 22.96 95.65 ± 52.16* 3.45 0.04
VD(ng/mL) 18.75 ± 6.33 19.19 ± 7.86 12.21 ± 0.50 2.06 0.13
LOHS(day) 17.47 ± 12.39 23.43 ± 4.86 28.00 ± 15.09 2.06 0.13
FT3(nmol/L) 3.63 ± 0.97 3.67 ± 1.21 2.52 ± 0.50 2.49 0.08
FT4(pmol/L) 16.03 ± 3.31 16.13 ± 3.59 17.40 ± 3.03 0.32 0.72
TSH(mIU/L) 2.31 ± 1.61 4.09 ± 2.47 4.59 ± 1.58* 6.48 0.01

DOD, duration of diabetes; LOHS, length of hospital stay: *One-way ANOVA showed significant differences only in CRP and TSH among the three groups (P < 0.05). Post-hoc analysis (LSD-t test): *P < 0.05 compared to the non-amputation group.