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. Author manuscript; available in PMC: 2026 Jul 1.
Published in final edited form as: Neuroscience. 2026 Jun 9;610:147–162. doi: 10.1016/j.neuroscience.2026.06.002

Fig. 3. Iba1-labeling in the hippocampus from Oxy CIS female and male rats.

Fig. 3.

a-d. Representative micrographs showing Iba1 labeling in the CA1 of Sal CIS female (a), Oxy CIS female (b), Sal CIS Male (c), and Oxy CIS male (d) rats. e. CA1: Sal CIS females compared to Sal males had lower Iba1 densities in SR. Oxy CIS females compared to Sal CIS females and Oxy CIS males show higher Iba1 densities in SO, SP, and SR. Moreover, Oxy CIS males compared to Sal CIS males had lower Iba1 densities in SO. f-i. Representative micrographs showing Iba1 labeling in CA3b of Sal CIS female (f), Oxy CIS female (g), Sal CIS male (h), and Oxy CIS male (i) rats. j. CA3b: Sal CIS females compared to Sal CIS males had higher Iba1 densities in SP and SLu. Oxy CIS females compared to Sal CIS females had higher Iba1 densities than in SR. Data are expressed as mean +/− SEM, N = 5–6 rats/grp. *p < 0.05, **p<0.01, ***p<0.001. Scale Bars: a-d & f-i, 100 microns