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. 2026 Jun 30;18:419. doi: 10.1007/s40820-026-02265-x

Table 3.

Application-level evaluation metrics and current maturity indicators for representative AI-integrated soft electronic systems

Application AI metric Comfort/interface Stability/duration Current stage/limitation References
Anomaly detection (dry ear-EEG) 93.2–93.3% drowsiness accuracy User-generic dry in-ear electrodes; compact wireless form factor 35 h dataset across 9 subjects Population-trained neural monitoring is feasible, but validation remains task-specific [193]
Biomarker profiling (reusable hydrogel EEG) 91.38% attention classification 310 ohms impedance; reusable adhesion 104 kPa (30 cycles) 20,000 cycle stability, 14-day signal fidelity 25.2 dB Strong interface maturity, but cohort and task remain limited [90]
Biochemical sensing (multiplex microneedle eMPatch) 0.996 classification, R2 = 0.977 30 min skin recovery; no visible irritation; no erythema/inflammation after 7 d  > 88% retention over 120 min, RSD < 2.64%, stable under bending/twisting Mechanically robust, but evidence is still largely preclinical [194]
Closed-loop therapy (a-Heal wound platform) ML-guided stage diagnosis + adaptive EF/drug control Portable, wireless, bandage-integrated wearable Imaging + therapy updated every 2 h over day 0–7 Proof-of-concept closed loop; longer protocols limited by device failure/external power [195]
Immersive HMI (motion tracking + haptics) ~ 97% classification, AUPRC 0.994, ~ 40 ms inference No irritation after 24 h; no redness/itching/discomfort 24.5–27 °C epidermal temperature, ~ 160 h transmission Strong wearability benchmark, but orientation/placement changes still matter [33]
Interactive HMI (organogel pressure HMI) 98% alphabet recognition Self-adhesive, biocompatible organogel Stable for 1 month, 40–95% RH, − 20 to 45 °C Promising robust HMI, but task complexity remains limited [196]
Embodied soft robot (AI-embodied FEbot) Onboard self-learning/hyperdimensional computing Multimodal proprioception + exteroception 87.6 mm/s vertical climbing, 5.1 × payload, survives 500 kg compression Embodied intelligence is advancing, but standardized long-duration autonomy metrics are still lacking [197]

For wearable healthcare/HMI rows, comfort/interface emphasizes conformability, irritation, thermal burden, low impedance, or minimally invasive coupling. For soft robots, the analogous maturity indicators are mechanical robustness, perturbation tolerance, payload, and sustained closed-loop operation

AUPRC Area Under the Precision-Recall Curve, RSD Relative Standard Deviation, RH Relative Humidity, EF Electric Field