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. 2006 Jan 17;34(2):407–416. doi: 10.1093/nar/gkj445

Figure 7.

Figure 7

Est3 mutants retaining the ability to dimerize show telomere shortening in ectopic co-expression with wild-type. Both wild-type EST3 (in pRS316 CEN plasmid) and mutant est3 (in pRS315 CEN plasmid) were co-introduced into est3 deletion cells, telomere Southern blot was performed, the isogenic transformants were as following: wt (wild-type), wt&wt, wt&est3-D49A, wt&est3-K68A, wt&est3-K71A, wt&est3-D86A, wt&est3-F103A, wt&est3-T115A.