Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
est3 mutants and telomere phenotype
| Type | Telomere phenotype | Amino acid substitution |
|---|---|---|
| I | Cell senescence | D86A |
| II | Telomere shortening | K3A, D49A, K68A |
| K71A, F72A, A82E | ||
| S87A, F95A, F103A | ||
| E104A, T115A, D166A | ||
| III | Little or no telomere defect | S8A, P12A, K23A |
| I42E, L45E, K47A | ||
| T58A, I59E, P63A | ||
| F66A, D77A, K79A | ||
| C99E, L119E, L127A | ||
| Y129A, S133A, K140A | ||
| S147A, V154E, Q159A | ||
| F163A, T173A, K179A |
