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. 2026 Jun 19;13:1848260. doi: 10.3389/fmed.2026.1848260

Table 2.

Model fit statistics for latent class analysis of inflammatory profiles.

No. of classes AIC BIC Log-likelihood Entropy BLRT LR BLRT P Class proportions, %
2 7,081.4 7,229.3 −3,503.7 0.9556 - - 34.3/65.7
3 6,815.1 7,038.9 −3,351.5 0.9288 304.37 < 0.001 29/29.8/41.3
4 6,668.4 6,968.1 −3,259.2 0.9216 184.66 < 0.001 15.5/25.4/29.1/30
5 6,591.5 6,967.2 −3,201.8 0.9246 114.87 < 0.001 11.4/14.6/19.5/27.2/27.2

AIC, Akaike information criterion; BIC, Bayesian information criterion; BLRT, bootstrap likelihood ratio test. Indicators included: WBC, CRP, PCT, NLR, PLR, SII, temperature, duration of symptoms, and age (tertile-categorized). Although the 5-class model demonstrated the lowest AIC/BIC values, the 3-class model was selected as the final solution based on highest entropy (0.929), clinical interpretability, and avoidance of over-fragmentation (see Section 3.2).