Table 3.
Comparison of clinical characteristics and outcomes across latent inflammatory classes.
| Characteristic | Low inflammation (n = 118) | Moderate inflammation (n = 164) | High inflammation (n = 120) | P value |
|---|---|---|---|---|
| Inflammatory markers | ||||
| WBC, × 109/L | 8.6 (6.4–10.3) | 16.5 (13.0–19.9) | 17.8 (14.4–21.0) | < 0.001 |
| CRP, mg/L | 4.9 (0.7–16.2) | 82.1 (29.7–133.8) | 74.9 (23.0–135.8) | < 0.001 |
| PCT, ng/mL | 0.2 (0.1–0.5) | 0.6 (0.3–3.6) | 0.7 (0.3–7.6) | < 0.001 |
| NLR | 1.8 (1.2–3.2) | 8.1 (6.0–9.5) | 16.6 (13.5–25.0) | < 0.001 |
| PLR | 118.0 (98.1–139.2) | 182.9 (147.9–222.6) | 363.3 (271.2–496.2) | < 0.001 |
| SII | 538.2 (375.4–939.3) | 2552.1 (1873.4–3067.4) | 5535.9 (4192.0–7923.3) | < 0.001 |
| Temperature, °C | 36.7 (36.5–36.9) | 37.6 (36.6–39.0) | 37.0 (36.6–38.5) | < 0.001 |
| Duration of symptoms, days | 3.0 (1.0–7.0) | 3.0 (1.0–6.0) | 1.8 (1.0–3.0) | < 0.001 |
| Age, years | 10.0 (8.0–12.0) | 8.0 (6.0–10.2) | 8.0 (6.8–10.0) | < 0.001 |
| Clinical and surgical outcomes | ||||
| Hospital stay, days | 4.0 (3.0–5.0) | 7.0 (5.0–9.0) | 7.0 (6.0–9.0) | < 0.001 |
| Operation time, min | 35.0 (30.0–45.0) | 55.0 (39.0–80.0) | 55.0 (40.0–70.0) | < 0.001 |
| Bleeding, mL | 1.0 (1.0–2.0) | 2.0 (1.0–5.0) | 2.0 (1.0–2.0) | < 0.001 |
| Appendix length, mm | 55.0 (50.0–70.0) | 60.0 (45.0–65.5) | 60.0 (45.0–70.0) | 0.886 |
| Appendix diameter, mm | 7.0 (5.2–8.0) | 8.0 (7.0–10.0) | 10.0 (7.0–11.2) | < 0.001 |
| Albumin, g/L | 42.5 (40.7–44.3) | 39.5 (35.5–42.2) | 41.5 (38.4–43.3) | < 0.001 |
Data are presented as median (Q1-Q3). P values were calculated using Kruskal-Wallis test. WBC, white blood cell; CRP, C-reactive protein; PCT, procalcitonin; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index.