Table 1. Synthesis of propargyl ethers and esters (8 → 7).

Compound	Base	X	Solvent	t, h	T, °C	Yield, %
7a	K2CO3	Br	Me2CO	25.5	56 → r.t.	95
7b	K2CO3	Br	Me2CO	17.5	r.t.	94
7c	K2CO3	OMs	DMF	24	80	33
7d	K2CO3	Br	DMF	24	60	24
7e	K2CO3	Br	DMSO	24	65	43
7fa	NaOH	Br	DMF	20	r.t	14
7g	NaH	Br	DMF	17.5	0 → 40	57
7h	NaOH	Br	DMF : Hex = 4 : 3	12	r.t	57
7i	NaOH	Br	DMF : Hex = 1 : 1	24	r.t	23

^aKI (0.1 eq.) was added.