Table 2. Frequency and prevalence ratios of cardiac events in the period 2017–2021 among 5-year survivors of childhood cancer and a matched*1 comparison group in Germany.
| Frequency of cardiac disease*2, *3 N (%) | |||
|---|---|---|---|
| Five-year survivors (N = 11 863) | Comparison group*1 (N = 35 589) | Prevalence ratio [95%CI] | |
| Sex | |||
| Female | 383 (7.3) | 445 (2.8) | 2.6 [2.3–3.0] |
| Male | 374 (5.6) | 449 (2.3) | 2.5 [2.2–2.9] |
| Age at 1 January 2017 (years) | |||
| 5 to < 10 | 61 (7.7) | 25 (1.1) | 7.3 [4.6–11.6] |
| 10 to < 20 | 289 (6.5) | 282 (2.1) | 3.1 [2.7–3.7] |
| 20 to < 30 | 294 (5.7) | 392 (2.6) | 2.2 [1.9–2.6] |
| ≥ 30 | 113 (7.7) | 195 (4.4) | 1.8 [1.4–2.2] |
| Total | 757 (6.4) | 894 (2.5) | 2.5 [2.3–2.8] |
*1
Matching criteria: age, sex, region of residence, duration of insurance
*2
Defined according to the International Classification of Diseases (ICD-10): congestive heart failure/cardiomyopathy (I42); valvular heart disease (I34–I39); cardiac arrhythmia (I47–I49); pericardial disease (I31); coronary heart disease/ischemic heart disease (I20–I25); cardiac insufficiency (I50)
*3
At least one specific cardiac diagnosis in at least two quarters during the SHI insurance period 2017–2021
CI, Confidence interval; SHI, statutory health insurance carrier