Table 3:

Parameters Evaluated in Univariable and Multivariable Analysis and Their Performance Metrics in the Differentiation of Indolent Versus Aggressive Renal Neoplasms

Analysis and Model	AUC	P Value*	Sensitivity (%)	Specificity (%)
Univariable analysis
ADC	0.38 (0.00, 0.73)	…	39	64
RBF	0.62 (0.08, 1.00)	.20	75	59
T1	0.39 (0.00, 0.72)	.54	39	68
T2	0.83 (0.50, 1.00)	.02	82	83
Multivariable analysis
ADC + RBF	0.51 (0.00, 0.90)	…	60	59
T1 + T2	0.89 (0.60, 1.00)	.06	86	93
ADC + RBF + T1	0.42 (0.00, 0.80)	.50	49	57
ADC + RBF + T2	0.75 (0.38, 1.00)	.13	80	73
ADC + RBF + T1 + T2	0.83 (0.50, 1.00)	.07	79	87

Note.—Data in parentheses are 95% CIs. MR fingerprinting–derived T1 and T2 relaxation times provided complementary information, yielding an area under the receiver operating characteristic curve (AUC) of 0.89 in this analysis. ADC = apparent diffusion coefficient, RBF = renal blood flow.

^*P values for the AUC comparison are presented, using the ADC-only model as the reference for the univariable analysis and the ADC + RBF model as the reference for the multivariable analysis.