TABLE 3.
Clinical parameter differences between individuals with elevated and hypertensive stage 1/hypertensive stage 2 disease and normotensive individuals with T1D
| Variable | Elevated and hypertensive stage 1 | ρ | Normotensive | ρ | Hypertensive stage 2 |
|---|---|---|---|---|---|
| N | 14 | 15 | 11 | ||
| Age (years) | 24.6 ± 3.3 | ns | 25.1 ± 2.1 | ns | 24.1 ± 2.6 |
| Age at diagnosis (years) | 9.6 ± 4.3 | ns | 9.1 ± 3.3 | ns | 6.9 ± 3.5 |
| Diabetes duration (years) | 14.7 ± 2.5 | ns | 15.1 ± 3.8 | ns | 17.0 ± 3.1 |
| BMI (kg/m2) | 24.5 ± 3.9 | ns | 23.7 ± 2.5 | ns | 24.6 ± 4.4 |
| Waist circumference (cm) | 84.5 ± 13.3 | ns | 79.5 ± 7.7 | ns | 83.6 ± 12.1 |
| HbA1c (mmol/mol) | 63 ± 12 | ns | 60 ± 8 | ns | 75 ± 26 |
| HbA1c (%) | 7.9 ± 1.1 | ns | 7.6 ± 0.8 | ns | 9.0 ± 2.4 |
| Total Cholesterol (mmol/l) | 4.2 ± 0.9 | ns | 4.1 ± 0.6 | 0.006 | 5.1 ± 1.0 |
| HDL-c (mmol/l) | 1.8 ± 0.5 | ns | 1.5 ± 0.3 | ns | 1.8 ± 0.7 |
| LDL-c (mmol/l) | 3.0 ± 1.0 | ns | 2.5 ± 0.6 | 0.038 | 3.1 ± 0.8 |
| Triglycerides (mmol/l)a | 0.87 (0.39, 1.23) | ns | 0.79 (0.38, 2.37) | ns | 1.14 (0.39, 3.50) |
| Apolipoprotein B (g/l) | 0.9 ± 0.2 | ns | 0.8 ± 0.2 | 0.038 | 1.0 ± 0.2 |
| Apolipoprotein A1 (g/l) | 1.6 ± 0.3 | ns | 1.5 ± 0.2 | ns | 1.8 ± 0.5 |
| Creatinine (μmol/l) | 69.3 ± 11.5 | ns | 69.4 ± 12.1 | ns | 70.5 ± 9.4 |
| eGFR | 117.8 ± 10.4 | ns | 112.5 ± 17.7 | ns | 112.0 ± 14.8 |
| u-ACR (mg/mmol)a | 0.50 (0.20, 7.70) | ns | 0.40 (0.20, 1.80) | ns | 0.90 (0.30, 232.60) |
| PWV (m/s) | 8.2 ± 1.3 | ns | 7.7 ± 0.7 | ns | 8.1 ± 1.3 |
The data are presented as the mean ± SDs, analyzed using independent samples t-tests.
a
Presented as the median (minimum and maximum), analyzed by the Mann–Whitney U test.