Table 3.
List of previously unknown genes that can be annotated using GPPP
| E. coli gene name (Genbank id) | Previous annotation | Predicted function by GPPP | Additional evidences from BLAST/Pfam/COG |
| b1681 (1787971) | Hypothetical protein | Transport system, membrane protein | COG0719: predicted membrane components of ABC-transporter SufB |
| b1683 (1787973) | Hypothetical protein | Transport system, membrane protein | |
| b2608 (1788960) | Hypothetical protein | RNA processing | Pfam domain: RimM. RimM is essential for processing of 16S rRNA. |
| b2766 (1789125) | Hypothetical protein | Flavorprotein, electron transport | COG0644:dehydrogenase/flavoprotein |
| b0407 (1786608) | Hypothetical protein | Protein secretion | Pfam domain: DUF219, (uncharacterized secreted protein) |
| b1395 (1787661) | Putative enzyme | Part of fad operon | BLAST: 3-hydroxyacyl-CoA dehydrogenase |
| b2341 (1788682) | Putative enzyme | Part of fad operon | BLAST: 3-hydroxyacyl-CoA dehydrogenase; enoyl-CoA isomerase/hydrotase |
| b0284 (1786478) | Hypothetical protein | Neighboring with xanthine dehydrogenase gene (b0286) | BLAST: Putative oxidoreductase |
| b2866 (1789230) | Hypothetical protein | Neighboring with xanthine dehydrogenase (b2868) | BLAST: Probable aldehyde oxidase and xanthine dehydrogenase family protein |
| b1674 (1787963) | Hypothetical protein | Oxidoreductase | BLAST: Aldehyde ferredoxin oxidoreductase |
| b2371 (1788714) | Hypothetical protein | Enzyme in carnitine metabolism | Pfam domain: CAIB-BAIF, domain involved in carnite metabolism |
| b2374 (1788717) | Hypothetical protein | Enzyme in carnitine metabolism | Pfam domain: CAIB-BAIF, domain involved in carnite metabolism |
| b2125 (2367130) | Hypothetical protein | Response regulator in 2-component system | Pfam domains: response-reg, REC probable cheY receiver domain |
| b0936 (1787167) | Hypothetical protein | Transport system | Pfam domain: PBPb, transport system related |
| b2075 (1788390) | Hypothetical protein | Integral transmembrane protein | Pfam: ACR_tran, SecD_SecF, Patched, transmembrane domain related |
| b2076 (1788391) | Hypothetical protein | Integral transmembrane protein | Pfam: ACR_tran |
| b1086 (1787327) | Hypothetical protein | RNA processing | BLAST: RNA pseudouridylate synthase |