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. 2026 Jun 25;13:1880853. doi: 10.3389/fnut.2026.1880853

Table 1.

RSM-predicted responses, including the optimum (fit) and confirmatory replicate (uncoded units).

Entry X1 (temp, °C) X2 (time, min) X3 (amp, %) TPC exp (mg GAE/100 ml) TPC Pred FRAP exp (mmol TE/L) FRAP pred
1 45 6.00 70.00 143.91 143.50 12.04 11.92
2 50 8.00 80.00 137.30 139.97 10.56 10.86
3 45 6.00 90.00 107.84 108.97 10.65 10.56
4 45 10.00 90.00 105.95 106.15 9.89 9.79
5 50 12.00 80.00 95.94 95.28 8.43 8.32
6 50 8.00 60.00 113.34 113.21 10.23 10.12
7 55 6.00 70.00 126.71 127.88 11.57 11.69
8 55 10.00 70.00 101.14 101.38 9.24 9.33
9 55 6.00 90.00 139.21 138.97 11.70 11.59
10 50 8.00 80.00 140.38 139.97 10.95 10.86
11 50 8.00 80.00 139.94 139.97 10.95 10.86
12 55 10.00 90.00 118.17 119.97 9.45 9.58
13 50 4.00 80.00 124.10 124.59 11.34 11.45
14 50 8.00 80.00 141.71 139.97 11.06 10.86
15 50 8.00 100.00 97.31 97.27 8.90 9.00
16 40 8.00 80.00 135.83 135.76 12.44 12.54
17 60 8.00 80.00 134.06 133.96 12.22 12.10
18 50 8.00 80.00 137.74 139.97 10.77 10.86
19 50 8.00 80.00 141.71 139.97 10.90 10.86
20 45 10.00 70.00 131.56 133.18 10.67 10.80
OPT (fit) 40 6.75 64.04 154.63 13.25
OPT (exp rep.) 40 6.75 64.04 149.77 12.86

X1, temperature (°C); X2, processing time (min); X3, ultrasound amplitude (%); FRAP, ferric reducing antioxidant power; TPC, total phenolic content; TE, Trolox equivalents; GAE, gallic acid equivalents; Exp, experimental; Pred, predicted; RSM, response surface methodology.