Fig. 7. (A) Superimposition of the native (yellow) and a complex (blue) protomer showing the rigid body displacement of the domains III and IV. The red box marks the centre of the hinge point. (B) Close-up stereoview of (A) showing the reaction centre with a nucleotide in the active site. Phe328 flipping by 90° causes the displacement of Pro327, Met330, Val331 and all following residues of the molecule.