Table 2.
Estimated 8-year changes in blood pressure, antihypertensive medication and renal function in patients who completed a prospective follow-up visit (n = 27)
| Effect estimate1 | 95% confidence interval | P value | |
|---|---|---|---|
| Blood pressure2 | |||
| 24 h ambulatory systolic blood pressure (mmHg) | −19.5 | −26.7, −12.4 | <0.001 |
| 24 h ambulatory diastolic blood pressure (mmHg) | −9.5 | −14.5, −4.4 | 0.001 |
| Daytime ambulatory systolic blood pressure (mmHg) | −21.6 | −29.0, −14.3 | <0.001 |
| Daytime ambulatory diastolic blood pressure (mmHg) | −12.1 | −17.7, −6.6 | <0.001 |
| Nighttime ambulatory systolic blood pressure (mmHg) | −13.4 | −22.1, −4.7 | 0.004 |
| Nighttime ambulatory diastolic blood pressure (mmHg) | −5.4 | −10.3, −0.5 | 0.03 |
| Office systolic blood pressure (mmHg) | −22.1 | −34.3, −9.8 | 0.001 |
| Office diastolic blood pressure (mmHg) | −11.2 | −16.9, −5.5 | 0.001 |
| Antihypertensive medication | |||
| Number of defined daily dosages | −1.7 | −2.8, −0.6 | 0.003 |
| Number of classes | −0.3 | −0.9, 0.2 | 0.21 |
| Renal function | |||
| Estimated glomerular filtration rate (ml/min/1.73m2) | −8.9 | −13.2, -4.7 | <0.001 |
1Inverse probability weighting has been implemented in all analyses to adjust for loss-to-follow-up
2All blood-pressure outcomes analyses have been adjusted for changes in defined daily dosages of antihypertensive drugs over time