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. 1976 Mar;16(3):199–207. doi: 10.1016/S0006-3495(76)85681-0

Transport calculations for light scattering in blood.

G D Pedersen, N J McCormick, L O Reynolds
PMCID: PMC1334832  PMID: 1252576

Abstract

In vivo measurement of the oxygen saturation levels in blood may be obtained from relative amounts of backscattered monochromatic light at two different wavelengths, as measured with a fiber-optic catheter oximeter. Because of the short mean free path length of light in blood, the backscattering can be well approximated by a previously-derived, one-wavelength transport theory solution for the half-space searchlight problem. This solution, unlike simple diffusion approximations has the advantage that the boundary condition describing illumination of a localized area of blood by a monodirectional light beam can be rigorously satisfied. Sample calculations using the solution are compared with experimental values of the reflectance of blood.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson N. M., Sekelj P. Light-absorbing and scattering properties of nonhaemolysed blood. Phys Med Biol. 1967 Apr;12(2):173–184. doi: 10.1088/0031-9155/12/2/303. [DOI] [PubMed] [Google Scholar]
  2. Cohen A., Longini R. L. Theoretical determination of the blood's relative oxygen saturation in vivo. Med Biol Eng. 1971 Jan;9(1):61–69. doi: 10.1007/BF02474405. [DOI] [PubMed] [Google Scholar]
  3. ENSON Y., BRISCOE W. A., POLANYI M. L., COURNAND A. In vivo studies with an intravascular and intracardiac reflection oximeter. J Appl Physiol. 1962 May;17:552–558. doi: 10.1152/jappl.1962.17.3.552. [DOI] [PubMed] [Google Scholar]
  4. Johnson C. C. Optical diffusion in blood. IEEE Trans Biomed Eng. 1970 Apr;17(2):129–133. doi: 10.1109/tbme.1970.4502711. [DOI] [PubMed] [Google Scholar]
  5. KAPANY N. S., SILBERTRUST N. FIBRE OPTICS SPECTROPHOTOMETER FOR IN VIVO OXIMETRY. Nature. 1964 Oct 10;204:138–142. doi: 10.1038/204138a0. [DOI] [PubMed] [Google Scholar]
  6. LOEWINGER E., GORDON A., WEINREB A., GROSS J. ANALYSIS OF A MICROMETHOD FOR TRANSMISSION OXIMETRY OF WHOLE BLOOD. J Appl Physiol. 1964 Nov;19:1179–1184. doi: 10.1152/jappl.1964.19.6.1179. [DOI] [PubMed] [Google Scholar]
  7. Mook G. A., Osypka P., Sturm R. E., Wood E. H. Fibre optic reflection photometry on blood. Cardiovasc Res. 1968 Apr;2(2):199–209. doi: 10.1093/cvr/2.2.199. [DOI] [PubMed] [Google Scholar]
  8. TWERSKY V. Multiple scattering of waves and optical phenomena. J Opt Soc Am. 1962 Feb;52:145–171. doi: 10.1364/josa.52.000145. [DOI] [PubMed] [Google Scholar]
  9. Zdrojkowski R. J., Pisharoty N. R. Optical transmission and reflection by blood. IEEE Trans Biomed Eng. 1970 Apr;17(2):122–128. doi: 10.1109/tbme.1970.4502710. [DOI] [PubMed] [Google Scholar]

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