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Mechanistic hypotheses for the origin of cMoMa
(A) Colored clones indicate lineage segregation through the blastocyst stage and into both twins.
(B) Option 2: a singular event. A single mutational event occurs before sister-chromatid formation. Asymmetric processing during repair creates two distinct 1-bp deletions that are subsequently segregated to opposite sister chromatids after DNA replication.
