Abbreviation	Full term
AIOM	Associazione Italiana di Oncologia Medica (Italian Association of Medical Oncology)
AJCC	American Joint Committee on Cancer
ANZMTAG	Australia and New Zealand Melanoma Trials Alliance Guidelines Group
ASCO	American Society of Clinical Oncology
ASCO/SSO	American Society of Clinical Oncology/Society of Surgical Oncology
BRAF	v-Raf murine sarcoma viral oncogene homolog B1
CD8	Cluster of differentiation 8
CDKN2A	Cyclin-dependent kinase inhibitor 2A
cfDNA	Cell-free DNA
CLND	Completion lymph node dissection
CNS	Central nervous system
CR	Complete response
CTC	Circulating tumor cell
ctDNA	Circulating tumor DNA
CTLA-4	Cytotoxic T-lymphocyte-associated protein 4
DMFS	Distant metastasis-free survival
DTIC	Dacarbazine
EADO	European Association of Dermato-Oncology
EFS	Event-free survival
EMA	European Medicines Agency
EMEA	European Agency for the Evaluation of Medicinal Products
EORTC	European Organisation for Research and Treatment of Cancer
ESMO	European Society for Medical Oncology
FAK	Focal adhesion kinase
FDA	Food and Drug Administration
GEP	Gene expression profiling
GM-CSF	Granulocyte-macrophage colony-stimulating factor
HD IL-2	High-dose interleukin-2
HR	Hazard ratio
ICI	Immune checkpoint inhibitor
ICP	Immune checkpoint
IL-2	Interleukin-2
ILI	Isolated limb infusion
ILP	Isolated limb perfusion
irAEs	Immune-related adverse events
iRECIST	Immune-response evaluation criteria in solid tumors
LAG-3	Lymphocyte activation gene-3
LDH	Lactate dehydrogenase
LM	Lentigo maligna
MAPK	Mitogen-activated protein kinase
MHC	Major histocompatibility complex
MHC-I	Major histocompatibility complex class I
MHC-II	Major histocompatibility complex class II
MMP	Matrix metalloproteinase
MMS	Mohs micrographic surgery
MPR	Major pathologic response
MSLT-II	Multicenter Selective Lymphadenectomy Trial II
MSS	Melanoma-specific survival
MTD	Maximum tolerated dose
NCCN	National Comprehensive Cancer Network
NGS	Next-generation sequencing
NSCLC	Non-small cell lung cancer
ORR	Objective response rate
OS	Overall survival
OV	Oncolytic virus
pCR	Pathologic complete response
PD-1	Programmed cell death protein 1
PD-L1	Programmed death-ligand 1
PFS	Progression-free survival
PI3K	Phosphatidylinositol-3-kinase
PV-10	Rose bengal disodium (PV-10)
qPCR	Quantitative polymerase chain reaction
RFS	Recurrence-free survival
RTK	Receptor tyrosine kinase
SLNB	Sentinel lymph node biopsy
SSO	Society of Surgical Oncology
SWOG	Southwest Oncology Group
T-VEC	Talimogene laherparepvec
TCR	T-cell receptor
TIL	Tumor-infiltrating lymphocyte
TLND	Therapeutic lymph node dissection
TME	Tumor microenvironment
TMZ	Temozolomide
TNF-$\alpha$	Tumor necrosis factor-alpha
WLE	Wide local excision