ADCC	Antibody-Dependent Cellular Cytotoxicity
ADCP	Antibody-Dependent Cellular Phagocytosis
Aire	Autoimmune Regulator
AJCC	American Joint Committee on Cancer
APC	Antigen-Presenting Cell
ARRIVE	Animal Research: Reporting of In Vivo Experiments
BRAF	v-Raf Murine Sarcoma Viral Oncogene Homolog B
CCL	C-C Motif Chemokine Ligand
CD	Cluster of Differentiation
CDKN2A	Cyclin-Dependent Kinase Inhibitor 2A
CI	Confidence Interval
CM	Cutaneous Melanoma
CTLA-4	Cytotoxic T-Lymphocyte-Associated Protein 4
ctDNA	Circulating Tumour DNA
CXCL	C-X-C Motif Chemokine Ligand
CXCR	C-X-C Motif Chemokine Receptor
DFS	Disease-Free Survival
DMFS	Distant Metastasis-Free Survival
DSP	Digital Spatial Profiling
ELISA	Enzyme-Linked Immunosorbent Assay
FcγR	Fc Gamma Receptor
FDA	U.S. Food and Drug Administration
FOXP3	Forkhead Box P3
Gal-3	Galectin-3
GZMA	Granzyme A
GZMB	Granzyme B
H&E	Hematoxylin and Eosin
HLA	Human Leukocyte Antigen
HPF	High-Power Field
HR	Hazard Ratio
iCAF	Inflammatory Cancer-Associated Fibroblast
ICI	Immune Checkpoint Inhibitor
IDO	Indoleamine 2,3-Dioxygenase
IFN-γ	Interferon Gamma
Ig	Immunoglobulin
IHC	Immunohistochemistry
IL	Interleukin
iNOS	Inducible Nitric Oxide Synthase
irAE	Immune-Related Adverse Event
IRS	Immunoreactive Score
I2	I-Squared (Heterogeneity Statistic)
JASP	Jeffreys’s Amazing Statistics Program
LAG-3	Lymphocyte Activation Gene 3
LDH	Lactate Dehydrogenase
MAIT	Mucosal-Associated Invariant T Cell
MAPK	Mitogen-Activated Protein Kinase
MCP-4	Monocyte Chemotactic Protein4
MDSC	Myeloid-Derived Suppressor Cell
MEK	Mitogen-Activated Extracellular Signal-Regulated Kinase
MELscore	Melanoma PD-L1 Expression Score
MHC	Major Histocompatibility Complex
MITF	Microphthalmia-Associated Transcription Factor
MPR	Major Pathological Response
mRNA	Messenger Ribonucleic Acid
NF1	Neurofibromin 1
NK	Natural Killer
NKT	Natural Killer T-Cell
NRAS	Neuroblastoma RAS Viral Oncogene Homolog
OPG	Osteoprotegerin
ORR	Objective Response Rate
OS	Overall Survival
OXPHOS	Oxidative Phosphorylation
PD-1	Programmed Cell Death Protein 1
PD-L1	Programmed Cell Death Ligand 1
PD-L2	Programmed Cell Death Ligand 2
PFS	Progression-Free Survival
PI3K	Phosphoinositide 3-Kinase
PP2A	Protein Phosphatase 2A
PRAME	PReferentially Expressed Antigen in Melanoma
PRF1	Perforin1
PRISMA	Preferred Reporting Items for Systematic Reviews and Meta-Analyses
pSTAT1	Phosphorylated Signal Transducer and Activator of Transcription-1
PTEN	Phosphatase and Tensin Homolog
Qe	Cochran’s Q (Heterogeneity Test)
Qm	Meta-regression Moderation Test Statistic
RFS	Recurrence-Free Survival
RNA-seq	RNA Sequencing
ROB	Risk of Bias
ROBINS-I	Risk of Bias in Non-Randomised Studies of Interventions
ROC AUC	Receiver Operating Characteristic Area Under The Curve
SHP-2	Src Homology 2 Domain-Containing Phosphatase 2
SMD	Standardized Mean Difference
sPD-1	Soluble Programmed Cell Death Protein 1
SR/MA	Systematic Review and Meta-Analysis
SYRCLE	Systematic Review Centre for Laboratory Animal Experimentation
T-VEC	Talimogene Laherparepvec
TAM	Tumour-Associated Macrophage
TCGA	The Cancer Genome Atlas
TCR	T-cell Receptor
TEM	T Effector Memory
TIGIT	T-cell Immunoreceptor With Ig And ITIM Domains
TIL	Tumour-Infiltrating Lymphocyte
TIM-3	T-cell Immunoglobulin and Mucin Domain-Containing Protein 3
TLS	Tertiary Lymphoid Structure
TMB	Tumour Mutational Burden
TME	Tumour Microenvironment
TNF-α	Tumour Necrosis Factor Alpha
TNFRSF9	Tumour Necrosis Factor Receptor Superfamily Member9
TP53	Tumour Protein p53
Treg	Regulatory T Cell
TUNEL	Terminal Deoxynucleotidyl Transferase dUTP Nick End Labeling
UV	Ultraviolet
VEGF	Vascular Endothelial Growth Factor
WHO	World Health Organization
ZAP-70	Zeta-Chain-Associated Protein Kinase 70
τ2	Tau Squared (Between-Study Variance)