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. 2026 Jun 24;15(13):1144. doi: 10.3390/cells15131144
IFN-I Type I Interferon
TNFR Tumor Necrosis Factor Receptor
TNF Tumor Necrosis Factor
IBD Inflammatory Bowel Disease
RNA-Seq RNA Sequencing
CD Crohn’s Disease
NR-CD Non-Responsive CD
R-CD Responsive CD
IEC Intestinal epithelial cells
IFNs Interferons
scRNA-Seq Single cell RNA Sequencing
TNFR1 TNF receptor 1
Wnt Wingless related integration site
TA cells Transit amplifying cells
WAE Wound-associated epithelium
KRT6 Keratin 6
KRT17 Keratin 17
CLU Clusterin
SCA1 Stem cell antigen 1
TACSTD2/TROP2 Tumor associated calcium signal transducer 2/Trophoblast cell surface antigen 2
ANXA1 Annexin A1
CXCL1 Chemokine (C-X-C motif) ligand 1
CXCL10 Chemokine (C-X-C motif) ligand 10
CXCL11 Chemokine (C-X-C motif) ligand 11
YAP/TAZ Yes-associated protein/Transcriptional coactivator with PDZ-binding motif
IL6 Interleukin 6
REG4 Regenerating islet derived family member 4
DUOX2 Dual oxidase 2
CCL20 C-C motif chemokine ligand 20
GLDN Gliomedin
OLFM4 Olfactomedin 4
MUC1 Mucin 1
TNIP3 Tumor Necrosis Factor Alpha-Induced Protein interacting protein 3
S100P S100 calcium binding protein P
DOCK4 Dedicator of cytokinesis 4
TNFR2 TNF receptor 2
PAFR Platelet activating factor receptor
EGFR Epidermal growth factor receptor
Src Proto-oncogene tyrosine-protein kinase Src
Rac1 Rac family small GTPase 1
PGE2 Prostaglandin E2
AOM/DSS Azoxymethane/dextran sulfate sodium
STAT1 Signal transducer and activator of transcription 1
p21/CDKN1A Cyclin dependent kinase inhibitor 1A
TP53/p53 Tumor protein p53
Apol9a/b Apolipoprotein L9a and L9b
ERK Extracellular signal regulated kinase
IEC Intestinal epithelial cell
Ifnar1 Interferon alpha and beta receptor subunit 1
CK1α Casein kinase 1 alpha
AREG Amphiregulin
NF-κB Nuclear factor kappa B
MAPK Mitogen activated protein kinase
IRF1 Interferon regulatory factor 1