| CVD | cardiovascular disease |
| CM | cardiomyocyte |
| hiPSC-CMs | human-induced pluripotent stem-cell-derived cardiomyocytes |
| CoA | acyl-coenzyme A |
| CPT-1 | carnitine palmitoyl transferase 1 |
| PDH | pyruvate dehydrogenase |
| SGLT1 | sodium/glucose cotransporter 1 |
| LDH | lactate dehydrogenase |
| MCT1 | monocarboxylate transporters |
| PDK4 | pyruvate dehydrogenase kinase 4 |
| DOX | doxorubicin |
| SREBF2 | sterol regulatory element-binding factor 2 |
| FNTB | β-subunit of farnesyltransferase |
| HIF1-α | hypoxia-inducible factor 1 α |
| GLUT | glucose transporter |
| ATM | ataxia telangiectasia mutated |
| BNIP3 | BCL2 interacting protein |
| H3K27ac | H3 lysine 27 acetylation |
| PPAR-α | peroxisome proliferator-activated receptor-α |
| AMPK | AMP-activated protein kinase |
| MIDAS | mitochondrial dysfunction-associated senescence |
| SASP | senescence-associated secretory phenotype |
| Il-6 | interleukin-6 |
| IL-1β | interleukin-1β |
| TNF-α | tumor necrosis factor-α |
| TGF β2 | transforming growth factor β2 |
| MMP3 | matrix metalloproteinase-3 |
| GM-CSF | granulocyte–macrophage colony-stimulating factor |
| MLC2 | myosin light chain 2 |
| ACTA1 | actin alpha 1 |
| MICOS | mitochondrial contact site and cristae organizing system |
| ECM | extracellular matrix |
| TCA | tricarboxylic acid |
| IRF3 | interferon regulatory factor 3 |
| EVs | extracellular vehicles |
| hMSC | human mesenchymal stem cells |
| ERK1/2 | extracellular signal-regulated kinase 1/2 |
| FAO | fatty-acid oxidation |
| GDF15 | growth/differentiation factor 15 |
| I/R | ischemia–reperfusion |
| ROS | reactive oxygen species |