Figure 1.

Diagram of phenotypes of wild-type and bld2-1 cells. The primary defect in bld2-1 cells is likely to be shortened centrioles with singlet microtubules. The consequences of this defect are failure to assemble flagella, disorganized and frayed rootlet microtubules, and defects in cleavage furrow placement. Not shown are defects in centrin assembly and premature initiation of the cleavage furrow.