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. 2026 Jun 26;27(13):5807. doi: 10.3390/ijms27135807
TCR T-cell receptor
AIRE AutoImmune REgulator gene
mTECs medullary Thymic Epithelial Cells
APECED Autoimmune PolyEndocrinopathy-Candidiasis-Ectodermal Dystrophy
APS1 Autoimmune Polyendocrine Syndrome Type 1
APC Antigen-Presenting Cell
DCs Peripheral tolerogenic Dendritic Cells
eTACs extraThymic AIRE-expressing Cells
IDO Indoleamine 2,3 dioxygenase
IL-10 Interleukin 10
PD-L1 Programmed Death-Ligand 1
MH class II Major Histocompatibility Complex Class II
Tregs T regulatory cells
ChIP Chromatin Immunoprecipitation
PBMCs Peripheral Blood Mononuclear Cells
HDs Healthy Donors
N/A Not available
TG Thyroglobulin
TSH Thyrotropin
TSH-R Thyrotropin Receptor
INS Insulin
ZnT8 Zinc Transporter 8
IgG Immunoglobulin G
AT Annealing Temperature
% input Percent Input
Des Desert
qRT-PCR Quantitative Real-Time PCR
moDCs Monocyte-derived Dendritic Cells
Tr1 Type 1 regulatory T-cell
NOD Non-Obese Diabetic mice
INF-γ Interferon gamma
TFN-α Tumor Necrosis Factor alpha
PD1 Programmed Death 1
LAG3 Lymphocyte Activation Gene 3
TIM3 T-cell Immunoglobulin and Mucin domain 3
MoAb Monoclonal Antibody
TRA Tissue-Restricted Antigens
PBS Phosphate Buffer Saline
RT Room Temperature
Min Minutes
ON Overnight
HIF1A Hypoxia-Inducing Factor 1A
pTG Thyroglobulin Promoter
pTSH-R Thyrotropin Receptor Promoter
pINS Insulin Promoter
pZnT8 Zinc Transporter 8 Promoter
TBS Tris-buffer saline