Table 2. MBC (mg/L) of synthesized DDSs against gram-negative and gram-positive bacteria.
|
Synthesized DDSs |
P. aeruginosa ATCC 27853 |
E. coli ATCC 25922 |
K. pneumoniae ATCC 4352 |
P. vulgaris ATCC 13315 |
E. faecalis ATCC 29212 |
S. epidermidis ATCC 12228 |
S. aureus ATCC 29213 |
A. baumannii ATCC 19606 |
MRSA ATCC 43300 |
|
ZIF-8 |
- |
- |
- |
- |
625 |
39.06 |
625 |
- |
- |
|
ZIF-8@TA |
- |
- |
- |
- |
625 |
78.12 |
1250 |
- |
- |
|
ZIF-8 @TA @Cu |
- |
- |
- |
1250 |
625 |
312.5 |
625 |
- |
- |
|
ZIF-8 @ TA @ CTX |
- |
- |
- |
- |
625 |
312.5 |
1250 |
- |
- |
|
ZIF-8 @TA @Cu@CTX |
- |
- |
- |
- |
156.25 |
19.53 |
1250 |
- |
- |
|
CTX |
8 |
0.6 |
0.06 |
16 |
1 |
1 |
2 |
32 |
8 |
|
Reference |
0.5a |
0.06a |
0.5a |
0.125a |
2a |
0.25a |
0.06a |
0.5a |
1b |
aMeropenem; bCiprofloxacin. ATCC, American Type Culture Collection; CTX, cefotaxime; DDSs, drug delivery systems; MBC, minimum bactericidal concentration; MRSA, methicillin-resistant S. aureus; TA, tannic acid; ZIF, zeolitic imidazolate framework; CU, copper ion.